Sarcoma Cancer is a rare disease, often misdiagnosed, often afflicting children and young adults.
The Karen Wyckoff Sarcoma Foundation is dedicated to Sarcoma Cancer research, support and education...and the fight to find a cure.

Welcome to Rein in Sarcoma

Though Sarcomas are rare, you are not alone in your battle against the disease. The Karen Wyckoff Rein in Sarcoma Foundation provides news, resources, and a way to connect to others with the disease. Since our inception in 2001, Rein In Sarcoma has had the opportunity to serve many individuals who, like you, have waged a personal war against this disease.

To learn more our mission, click on our video below.

For more background information about RIS, click here.

We thank you for the privilege of assisting you on your personal sarcoma journey.

  • Our Mission
  • Karen's Story
  • Contact Us
  • Patient and Family Support Programs
  • Coping with Cancer
  • Sarcoma Survivor Stories
  • Understanding Sarcoma Cancers
  • Local and National Resources
  • Sarcoma Patient Starter Notebook
  • For newly Diagnosed Sarcoma Patients
  • Understanding Sarcoma Cancers
  • Lumps & Bumps
  • Red Flags of Sarcoma Cancer
  • Educating the public and medical profession about the warning signs of sarcoma Cancers


  • Why support to Rein in Sarcoma?
  • Ways to Give
  • Named Tribute and Memorial Funds
  • Plan your own Fundraiser to Benefit Rein in Sarcoma

Thanks for Giving to the Max!

GiveMN Logo 2014

Thanks to all of you who made our 2015 Give to the Max efforts on Nov 12th a great sucess!   Because of the outpouring by both new and veteran donors we fully met our $10,000 challenge grant match raising a record $22,195 in just one day!&n

Walser Subaru "Shares the Love" with RIS

Walser - 2015 Share the Love

The Karen Wyckoff Rein in Sarcoma Foundation has been selected by Walser Subaru in Burnsville to be their local partner in Subaru's Share the Love Event through January 2. Learn more...

Striking Out Sarcoma

Park Tavern- Social 2015On the afternoon of Sunday, October 25, sarcoma patients, their loved ones and volunteers gathered at Park Tavern Bowling and Entertainment Center in St, Louis Park to “strike out” sarcoma. They enjoyed appetizers, a winning Viking’s game and bowling.

For some this was their second year attending the event. However, for others this was their first time attending the Fall Gathering. Both new and veteran attendees agreed that the event was an excellent way to meet others affected by sarcoma.

For the Zachs and Karens

Zach Sobiech and Karen Wyckoff

In October, The University of Minnesota Foundation highlighted the impact of Rein in Sarcoma and Zach Sobiech Fund in funding U researchers to identify potential proteins to target osteosarcoma treatments.

Article writer Nicole Endres writes "For Masonic Cancer Center scientists Branden Moriarity and David Largaespada, it’s about the Wyckoffs, the Sobiechs, and thousands of other families who are all too familiar with osteosarcoma and its devastating effects.

These families fuel the researchers’ passion to cure this often deadly form of bone cancer. And they recently got a little closer to that goal."  Read the University of Minnesota Foundation article.

Don’t Let Sarcoma Cancer Trick You!!

RIS Halloween CardTreat Yourself to some Knowledge

Save a life! Give the treat of knowledge about sarcoma cancers to trick or treaters this Halloween. Our highly creative RIS marketing team members, Chelsea Kennedy, Chelsey Olafson and Laurie Convey have come up with a nifty little give away for you to give with your candy treats this Halloween. Just print the RIS Halloween cards using a link below,  tape some candy on the card and give both a treat to the kids at your front door and a treat of knowledge about the "red flags" of sarcoma cancers for their parents. To learn more and download for easy printing on your printer, click here.